Laboratory of Alkaloids
WELCOME
To Our Institute Website!
Tbilisi State Medical University I.Kutateladze Institute of Pharmacochemistry

Director's Page

Laboratory of Akaliods Departments

laboratory of alkaloids 

 

The Laboratory of alkaloids was estabilished in 1965 based on the former Laboratory of Chemistry and Analysis, which  existed at the institute since 1933. It was managed on different times by different famous scientists: Nikoloz Maskhulia(1933-1942), N.Pliev (1942-1944) and Prof K.Mudjiri (1944-1981). Since 1981 Prof. V.Vachnadze is the Head of the Laboratory.

 

 

 (estabilished on 1965)

 

Field of Research :

Investigation of chemical structure of vegetable alkaloids.
Investigation of scientific background for the alkaloids isolation technology and analysis. 
Development of antihistamines and spasmolytics and also drugs acting on hematopoiesis,  tumor cells growth etc. .
Investigation of alkaloids for purposeful synthesis of biologically active compounds.
Main results:
More than 2000 plants of Georgian flora are investigated on composition of alkaloids. 400 species are determined containing alkaloids.
160 alkaloids, which represent derivates of indole, isochinoline, chinolizidine, taxons and steroidal alkaloids are isolated, identified, and structurally determined.
structure of 25 novel alkaloids has been determined.
Plants Vinca minor L. and Vinca herbaceae Wаldst. et Kit. are recommended for cultivation as a raw material for "Oxibral”, "Vincanor” – antiarrhythmic drug and stimulator of leicopoesis.
Plants containing alkaloids are defined, which are proposed as raw material of creating the drug of antitumorr, anticolinesterase, antihistamin,spasmolitic, antiaritmic aqtivity.  
The investigations for demonstrating the natural, biologically active reactives for using them in medical-biological investigations. 

The main results are published in 1 monography and 100 articles.
10 author certificates and 2 patents are issued.


 

Staff:

Head of labiratory:  Prof. Valentina Vachnadze.
Senior scientist: PHD L. Kincurashvili, Scientist: PHD T. Suladze, Scientist: PHD N. Vachnadze.

Administration

 

more



Laboratory of Steroids and Cardiac Glycosides

 

 

more



Laboratory of Medicinal Fermentology

more



Laboratory of Phenolic Compounds

 

more



Laboratory of Terpene Compounds

more



Laboratory of Plant Biopolymers

more



Laboratory of Akaliods

more



Laboratory of Lipids and Anthraquinones

more



Laboratory of Pharmaceutical Technology

more



Laboratory of Chemical Analysis and Standardisation

more



Laboratory of Chemical Modification of Natural Compounds

more



Laboratory of Pharmacobotany

more



Department of Pharmacology

more



Pilot Plant

more



Department of the Resource Management

 

more



Department of Scientific Information

 

 

more



Administrative support center


more



Storehouse

more



I.Kutateladze Institute of Pharmacochemistry © Copyright 2009-2014 All rights reserved